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. 2019 Dec 11;13:67. doi: 10.1186/s40246-019-0245-z

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© The Author(s). 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 5 — A proposed schematic diagram of miR-542-3p regulating the osteogenic transition of VSMCs in aging rats. MiR-542-3p expression is downregulated in oVSMCs. As a target of MiR-542-3p, the expression of BMP7 is upregulated which results in the osteogenic differentiation of VSMCs, suggesting the role of miR-542-3p in the vascular osteogenic transition in aging rat