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. Author manuscript; available in PMC: 2020 Dec 2.
Published in final edited form as: Curr Biol. 2019 Nov 7;29(23):4116–4123.e3. doi: 10.1016/j.cub.2019.10.011

Figure 3. The role of vm2 vulva muscles in regulating behavioral response to ascr#10.

Figure 3.

(A,B) Exploratory behavior of mutant hermaphrodites with defective muscle excitability. (C) Exploratory behavior in a mutant hermaphrodite in which vm2 vulva muscles do not synapse with HSN neurons. (D) Exploratory behavior in hermaphrodites with functional or silenced vm2 vulva muscles. In this experiment silencing commenced prior to initiation of egg-laying. Comparison of the two grey data series demonstrates that silencing of vm2 muscles increases exploratory movement. (E) Expression of tph-1::YFP in NSM and (F) HSN neurons in adults with functional or silenced vm2 vulva muscles. Arrows mark cell bodies. Anterior is to the left and ventral is down. In A-D, each square represents one animal. In E,F, each triangle represents one neuron. * p<0.05, ** p<0.01. See Figure S3 for additional related results and Data S1 for primary data and details of statistical analyses.