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. 2019 Dec 12;14(12):e0225275. doi: 10.1371/journal.pone.0225275

Fig 4. Proinflammatory factors in RAW 264.7 cells stimulated by LPS and treated with Vernonia polysphaera extract.

Fig 4

Levels of nitrite (A), proinflammatory cytokines (B-D), PGE-2 (E) in culture supernatants and mRNA expression of COX-2 (F) in cell culture treated with V. polysphaera (10, 50 or 100μg/mL) or dexamethasone, 100 μM. Data are representative of two independent experiments performed at least in quadruplicate. #P <0.001 compared with the group without stimulation or treatment; **p<0.01, ***p<0.001 compared with the stimulated and untreated group after Kruskal-Wallis analysis followed by Dunn’s multiple comparisons test.