Table 1. Biochemical quantification of liver and kidney parameters in the sera of BALB/c mice treated with Vernonia polysphaera hydroalcoholic extract by gavage for 15 days.
| Parameters | Unit | PBS | Vernonia polysphaera (mg/kg/day) | ||
|---|---|---|---|---|---|
| 50 | 250 | 500 | |||
| Creatinine | mg/dL | 0.20±0.000 | 0.15±0.0577 | 0.15±0.057 | 0.17±0.050 |
| Total bilirubin | mg/dL | 0.67±0.095 | 0.85±0.173 | 0.80±0.115 | 0.87±0.049 |
| Uric acid | mg/dL | 2.32±0.150 | 2.62±0.095 | 2.32±0.377 | 2.47±0.262 |
| Albumin | mg/dL | 4.12±1.577 | 2.85±0.129 | 3.25±1.066 | 3.12±0.537 |
| Urea | mg/dL | 42.27±2.715 | 61.40±1.202 | 60.25±7.747 | 67.57±3.756 |
| ALT | U/dL | 88.50±16.842 | 83.25±11.026 | 93.50±20.371 | 105.66±47.120 |
| AST | U/dL | 157.00±46.357 | 127.50±26.602 | 152.25±38.586 | 203.00±104.043 |
| Total protein | g/dL | 4.05±0.173 | 4.40±0.081 | 4.40±0.163 | 4.30±0.0816 |
ALT: Alanine aminotransferase, AST: Aspartate aminotransferase. Data represent mean ± standard deviation of two experiment performed in quintuplicate.