Table 1. Diagnostic studies.
Diagnostic studies | No. | % |
---|---|---|
Absent diurnal cortisol rhythma | 29/29 | 100 |
Failure to cortisol suppression by low dose dexamethasone | 18/22 | 82 |
Cortisol suppression by high dose dexamethasoneb | 23/27 | 85 |
Highc 24-h urine free cortisol | 21/23 | 91.3 |
aMeans of 2 serum cortisol values obtained at 0730–0800H and at 0000–0030H
The presence of diurnal cortisol rhythm defined when serum cortisol concentration reached its zenith in the morning (06.00–08.00 h) and its nadir in the night during the first half of normal sleep [2]
bCortisol reduced from baseline by ≥50%
cMore than 80 μg/m2 [2]