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. 2019 Nov 22;24:18.313. doi: 10.7812/TPP/18.313

Table 2.

Sigma 1 binding affinity of haloperidol, olanzapine, quetiapine, and risperidone

Compound Ki, nMa
Haloperidol 2.4
Olanzapine > 1000
Quetiapine > 1000
Risperidone > 1000
a

Sigma 1 selective radioligand ([3H](+)-pentazocine) binding competition assays were performed as described in the article by Thomas et al.13

Ki = binding affinity.