Skip to main content
. 2019 Dec 6;13:532. doi: 10.3389/fncel.2019.00532

Table 1.

Characteristic proteins of fibrocytes.

Protein Function Strongly expressing References
Caldesmon Calcium modulation Type III Mahendrasingam et al. (2011a)
S-100 Calcium modulation Type I, II and V Suko et al. (2000) and Mahendrasingam et al. (2011a)
Na, K-ATPase Sodium/potassium transport Type II and V Suko et al. (2000) and Mahendrasingam et al. (2011a)
Ca, ATPase Calcium transport Type I Ichimiya et al. (1994)
Na, K, Cl-cotransporter Sodium/potassium/chloride transport Type II, IV and V Qu et al. (2006)
NCBE Bicarbonate transporter Huebner et al. (2019)
GLAST Glutamate transport Jin et al. (2003) and Furness et al. (2009)
Kir5.1 Potassium channel Type II, IV, and V Hibino et al. (2004)
Ether-a-gogo Potassium channel Nie et al. (2005)
Kv3.1 Potassium channel So et al. (2001)
BK channels Potassium channel Liang et al. (2003)
ClC Chloride channels Qu et al. (2006)
Connexin 26, 30, 31, 43 Gap junction channel Forge et al. (2003)
AQP1 Water channel Type III Miyabe et al. (2002) and Mahendrasingam et al. (2011a)
Carbonic anhydrase Carbon dioxide-water converter Type I, III, IV and V Spicer and Schulte (1991)
Creatine kinase ADP-ATP cycling Type I, III, IV and V. Spicer and Schulte (1991)
Connective tissue growth factor (CTGF) Collagen metabolism Type IV Adams (2009)

Table illustrating some of the proteins known to be of functional relevance in fibrocytes and often used to characterize the different types.