Table 1.
Protein | Function | Strongly expressing | References |
---|---|---|---|
Caldesmon | Calcium modulation | Type III | Mahendrasingam et al. (2011a) |
S-100 | Calcium modulation | Type I, II and V | Suko et al. (2000) and Mahendrasingam et al. (2011a) |
Na, K-ATPase | Sodium/potassium transport | Type II and V | Suko et al. (2000) and Mahendrasingam et al. (2011a) |
Ca, ATPase | Calcium transport | Type I | Ichimiya et al. (1994) |
Na, K, Cl-cotransporter | Sodium/potassium/chloride transport | Type II, IV and V | Qu et al. (2006) |
NCBE | Bicarbonate transporter | Huebner et al. (2019) | |
GLAST | Glutamate transport | Jin et al. (2003) and Furness et al. (2009) | |
Kir5.1 | Potassium channel | Type II, IV, and V | Hibino et al. (2004) |
Ether-a-gogo | Potassium channel | Nie et al. (2005) | |
Kv3.1 | Potassium channel | So et al. (2001) | |
BK channels | Potassium channel | Liang et al. (2003) | |
ClC | Chloride channels | Qu et al. (2006) | |
Connexin 26, 30, 31, 43 | Gap junction channel | Forge et al. (2003) | |
AQP1 | Water channel | Type III | Miyabe et al. (2002) and Mahendrasingam et al. (2011a) |
Carbonic anhydrase | Carbon dioxide-water converter | Type I, III, IV and V | Spicer and Schulte (1991) |
Creatine kinase | ADP-ATP cycling | Type I, III, IV and V. | Spicer and Schulte (1991) |
Connective tissue growth factor (CTGF) | Collagen metabolism | Type IV | Adams (2009) |
Table illustrating some of the proteins known to be of functional relevance in fibrocytes and often used to characterize the different types.