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. 2019 Dec 6;9:1346. doi: 10.3389/fonc.2019.01346

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Copyright © 2019 Jiang, Li, Zhang, Huang, Zhang, Chen, Shang, Li and Nie.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Enriched flora in the healthy controls (NOR), familial NPC patients (NPC_F), and sporadic NPC patients (NPC_S) groups are represented in a cladogram. The origin of the tree (bacteria) showed in the central point, the larger circles centered on the center represent decreasing species levels from phylum to genus (phylum to genus: p, phylum; c, class; o, order; f, family; g, genus). The relative abundance of the flora is showed by each circle's diameter. (A) LEfSe analysis cladogram of intestinal flora among NOR, NPC_F and NPC_S groups at genus level. (B) LEfSe analysis cladogram of intestinal flora between NOR and NPC_F at genus level. (C) LEfSe analysis cladogram of intestinal flora between NOR and NPC_S at genus level.