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. 2019 Dec 12;8(Suppl 2):95–111. doi: 10.1007/s40120-019-00167-2

Table 1.

Lower detection limits of IMR assays for neurodegenerative disease markers

IMR assay targets Low detection limit (LoD), fg/ml
Aβ40 170
Aβ42 770
t-tau 26
p-tau 19.6
α-Synuclein 1.3
p-α-Synuclein-129 0.072
TDP-43 0.68
Neurofilament light chain (NFL) 3.3