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. 2019 Nov 18;404(7):815–823. doi: 10.1007/s00423-019-01836-4

Table 1.

Characteristics and risk for bleeding using uni- and multivariable logistic regression in patients operated for thyroid disease 2004–2010 in the Swedish quality register for thyroid surgery (SQRTPA)

Characteristics Patients with postoperative bleeding n = 174(%) Patients without postoperative bleeding n = 9320(%) Univariable analysis OR (CI) Multivariable analysis OR (CI) *P value
Age (years)
  <30 11 (6) 1156 (12) 1.00 1.00 <0.01
  30–50 43 (25) 3531 (38) 1.27 (0.65–2.48) 1.38 (0.70–2.71)
  50–70 81 (47) 3463 (37) 2.45 (1.30–4.63) 2.58 (1.33–5.00)
  >70 39 (22) 1170 (13) 3.50 (1.78–6.87) 3.62 (1.76–7.43)
Gender
  Female 115 (66) 7546 (81) 1.00 1.00 <0.01
  Male 59 (34) 1774 (19) 2.18 (1.58–2.99) 1.92 (1.38–2.67)
Indication for surgery
  Compression symptoms 69 (40) 3605 (39) 1.00 1.00 0.38
  Malignancy 27 (16) 1133 (12) 1.24 (0.79–1.95) 1.59 (0.84–3.03)
  Suspect for malignancy 41 (24) 2269 (24) 0.94 (0.63–1.39) 1.05 (0.68–1.62)
  Thyrotoxicosis 37 (21) 2200 (24) 0.87 (0.58–1.31) 1.30 (0.77–2.17)
  Missing 0 113 (1) na na
Type of operation
  Lobectomy 83 (48) 4471 (48) 1.00 1.00 0.68
  Thyroidectomy 77 (44) 3910 (42) 1.06 (0.77–1.43) 0.95 (0.62–1.43)
  Thyroid resection 11 (6) 636 (7) 0.93 (0.49–1.75) 0.87 (0.46–1.66)
  Other operations ** 3 (2) 303 (3) 0.53 (0.16–1.69) 0.41 (0.11–1.42)
Operation time (minutes)
  <60 5 (3) 488 (5) 1.00 1.00 0.24
  60–120 50 (29) 3055 (33) 1.59 (0.63–4.02) 1.45 (0.57–3.71)
  >120 57 (33) 2919 (31) 1.90 (0.76–4.77) 1.58 (0.60–4.13)
  Missing 62 (35) 2858 (31) 2.11 (0.84–5.29) 1.86 (0.72–4.74)
Gland weight (grams)
  <50 66 (38) 4149(45.5) 1.00 1.00 0.02
  50–200 41 (24) 2230 (24) 1.15 (0.78–1.71) 0.92 (0.59–1.42)
  200–500 14 (8) 378 (4) 2.34 (1.30–4.20) 1.46 (0.75–2.84)
  >500 2 (1) 37 (0.5) 3.39 (0.80–14.39) 2.34 (0.53–10.39)
  Missing 51 (29) 2528(27) 1.26 (0.87–1.83) 1.13 (0.76–1.67)
Substernal gland
  No 150 (86) 8532 (92) 1.00 1.00 0.01
  Yes 24 (14) 788 (8) 1.73 (1.11–2.68) 1.17 (0.71–1.95)
Sternotomy
  No 172(99) 9275(99.5) 1.00 1.00 0.21
  Yes 2 (1) 45 (0.5) 2.39 (0.57–9.95) 1.22 (0.27–5.51)
Lymph node dissection
  No 147 (84) 7854 (84) 1.00 1.00 0.94
  Yes 27 (16) 1466 (16) 0.98 (0.65–1.48) 0.77 (0.44–1.33)
Thymus operation
  No 173 (99.5) 9276 (99.5) 1.00 1.00 0.84
  Yes 1 (0.5) 44(0.5) 1.22 (0.16–8.89) 1.30 (0.17–9.85)
Previous thyroid operation
  No 157 (90) 8271 (89) 1.00 1.00 0.54
  Yes 17 (10) 1049 (11) 0.85 (0.51–1.41) 0.78 (0.44–1.39)

(*) P values present the results of comparison between groups.

(**) Other operations include missing information on operation type and other operation types than lobectomy, resection and total thyroidectomy.