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. 2019 Dec 12;9:18983. doi: 10.1038/s41598-019-55528-6

Figure 2.

Figure 2

FXR1 colocalizes with amyloid-specific dye Congo red in cortical neurons and demonstrates amyloid properties. (a) FXR1 is present in the perinuclear cytoplasm of cortical neurons and colocalizes with amyloid-specific dye Congo red. Scale bar, 10 µm. See also Supplementary Fig. S6. (b) FXR1 extracted from rat brain using immunoprecipitation binds Congo red and demonstrates yellow-green birefringence under polarized light. Scale bar, 100 μM (c) Fibrils of FXR1 extracted from rat brain using immunoprecipitation visualized by TEM. Scale bar, 200 nm.