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. 2019 Sep 6;14(1):53–66. doi: 10.1038/s41396-019-0502-0

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 6 — Measured total cobalamin (sum of both water-leachable and non-water-leachable cobalamin) and 5,6-dimethylbenzimidazole (DMB) concentrations in 40 soil samples (a), and cobalamin biosynthesis gene summary for 155 soil metagenomes (b). Cobalamin-producing genes in b were grouped as: Group A, corrin ring biosynthesis; Group B, final synthesis and repair; Group C, 5,6-dimethylbenzimidazole (DMB) synthesis. The 155 soil metagenomes are independent from the 40 soil samples used for cobalamin measurement. The center line in the box plot represents the median value