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. 2019 Dec 12;9:18937. doi: 10.1038/s41598-019-55454-7

Figure 2.

Figure 2

Fanconi anemia simulation. (A) The FA pathway. Nodes in orange contain known FA pathogenic genes. (B) The result of the LoF simulations over the different FA circuits. Over each gene column, the frequencies at which these genes have been found in the normal population (1000 genomes) with a pLoF mutation is represented.