Table 4.
Assessment Point 2 Volumes for Abstainers and Relapsers
| Region | Hemisphere and Subregion | CON (n = 33) | ABS (n = 39) | REL (n = 65) | ES CON vs. ABS | ES CON vs. REL | ES ABS vs. REL |
|---|---|---|---|---|---|---|---|
| Anterior Cingulate | Left Caudal | 1923 (454) | 1845 (460) | 1833 (456) | 0.17 | 0.20 | 0.03 |
| Right Caudal | 2214 (408) | 2182(405) | 2017 (402)$, & | 0.08 | 0.49 | 0.41 | |
| Left Rostral | 2546 (349) | 2345 (358)# | 2224 (355)$ | 0.57 | 0.90 | 0.34 | |
| Right Rostral | 1841 (345) | 1864 (340) | 1752 (438) | 0.07 | 0.23 | 0.29 | |
| Orbitofrontal | Left Medial | 4540 (552) | 4449 (629) | 4438 (629) | 0.15 | 0.16 | 0.02 |
| Right Medial | 5093 (641) | 4757 (636) | 4607 (637)$ | 0.53 | 0.76 | 0.24 | |
| Left Lateral | 9746 (854) | 9456 (917) | 9075 (910)$ | 0.33 | 0.73 | 0.42 | |
| Right Lateral | 9881 (835) | 9632 (880) | 9316 (873)$ | 0.29 | 0.65 | 0.36 | |
| Dorsal Prefrontal | Left Caudal Middle Frontal | 6598 (1216) | 6140 (1069) | 6069 (1070) | 0.45 | 0.50 | 0.07 |
| Right Caudal Middle Frontal | 5967 (1050) | 5995 (1021) | 5655 (1147) | 0.03 | 0.29 | 0.31 | |
| Left Rostral Middle Frontal | 15382 (1964) | 14872 (1975) | 14194 (1977)$ | 0.26 | 0.60 | 0.34 | |
| Right Rostral Middle Frontal | 16386 (2071) | 15440 (1905) | 14628 (1906)$ | 0.48 | 0.92 | 0.43 | |
| Left Superior Frontal | 22238 (1899) | 21499 (2003) | 20453 (2004)$, & | 0.38 | 0.89 | 0.52 | |
| Right Superior Frontal | 21353 (1956) | 20948 (1993) | 19959 (1995)$, & | 0.21 | 0.70 | 0.50 | |
| Precentral | Left | 12489 (1183) | 12671 (1156) | 11893 (1225)$, & | 0.15 | 0.50 | 0.65 |
| Right | 12742 (1149) | 12865 (1230) | 11935 (1157)$, & | 0.06 | 0.68 | 0.78 | |
| Insula | Left | 6543 (458) | 6219 (473)# | 6206 (470)$ | 0.70 | 0.72 | 0.03 |
| Right | 6507 (455) | 6156 (470)# | 6149 (467)$ | 0.76 | 0.76 | 0.01 | |
| Total Frontal Cortical | Left | 80291 (5186) | 77420 (5286) | 74636 (5290)$, & | 0.55 | 1.07 | 0.53 |
| Right | 80259 (5516) | 77762 (5528) | 74550 (5532)$, & | 0.45 | 1.03 | 0.58 |
Note. Mean (SD); ABS: Abstainers; CON: Non-smoking Light Drinking Controls; ES: Effect size; REL: Relapsers;
#
CON > ABS, p < .026;
$
CON > REL, p < .026;
&
ABS > REL, p < .026.