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. Author manuscript; available in PMC: 2020 Feb 23.
Published in final edited form as: Oncogene. 2019 Aug 23;38(50):7504–7520. doi: 10.1038/s41388-019-0967-3

Fig. 3.

Fig. 3

GLDC is required for the proliferation and tumorigenicity of MYCN-amplified neuroblastoma cell lines. a Cell growth assay of MYCN-amplified cell lines without (shGFP) or with GLDC knockdown (shGLDC). Error bars represent SEM (n = 5). b Microscopic image of IMR5 cells without or with GLDC knockdown. c-d Growth curves (c) and images (d) of SMS-KCNR xenografts without or with GLDC knockdown. Data were analyzed by multiple t test (Prism). e Survival curves for mice carrying SMS-KCNR xenografts without or with GLDC knockdown. Log-rank test p value is shown.