Table 2.
FDG and Dotatate findings for the study cohort
| ID | Prior Immunotherapy and Start Date | Cardiac FDG uptake (SUVmax) | Nodal FDG uptake (SUVmax) | Days to Dotatate | Cardiac Dotatate uptake (SUVmax) | Nodal Dotatate uptake (SUVmax) | Cardiac concordance | Nodal concordance |
|---|---|---|---|---|---|---|---|---|
| 1 | Methotrexate 2.5 mg weekly > 1 year | Focal (6.58) | Increased (8.4) | 139 | Focal (1.33) | Increased (1.86) | Concordant | Concordant |
| 2 | None | Multifocal (6.89) | Increased (11.47) | 35 | Multifocal (1.70) | Increased (2.74) | Concordant | Concordant |
| 3 | None | Focal on diffuse (10.97) | Increased (22.6) | 70 | Focal (2.05) | Increased (2.40) | Concordant | Concordant |
| 4 | None | Focal (4.15) | Increased (7.01) | 37 | Focal (1.09) | Increased (2.46) | Concordant | Concordant |
| 5 | None | Focal on diffuse (2.77) | Negative (2.10) | 22 | Heterogeneous (1.34) | Negative (0.97) | Concordant | Concordant |
| 6 | None | Focal on diffuse (5.22) | Negative (4.14) | 37 | Heterogenous (2.21) | Negative (1.84) | Concordant | Concordant |
| 7 | None | Multifocal (11.48) | Negative (2.01) | 51 | Diffuse intense (1.84) | Negative (1.19) | Concordant | Concordant |
| 8 | Prednisone 20 mg daily 5 days before Dotatate | Focal on diffuse (6.50) | Increased (4.47) | 61 | Negative (0.91) | Increased (1.79) | Discordant | Concordant |
| 9 | Methotrexate 15 mg weekly > 1 year | Focal on diffuse (9.18) | Increased (5.95) | 13 | Negative (0.99) | Increased (2.01) | Discordant | Concordant |
| 10 | Prednisone 15mg daily 5 months before FDG | Focal (2.33) | Negative (1.08) | 15 | Negative (1.28) | Negative (1.03) | Discordant | Concordant |
| 11 | Prednisone 15 mg daily 25 days before FDG | Focal on diffuse (7.85) | Negative (1.59) | 16 | Negative (1.11) | Negative (1.24) | Discordant | Concordant |
| 12 | None | Focal (5.91) | Negative (2.85) | 27 | Negative (1.19) | Negative (1.54) | Discordant | Concordant |
| 13 | None | Focal on diffuse (5.47) | Negative (2.0) | 55 | Negative (0.67) | Negative (1.38) | Discordant | Concordant |
| Total | 38% | 6.5 [5.2-7.9] | 4.1 [2.0-7.0] | 37 [25-55] | 1.28 [1.1-1.7] | 1.8 [1.2-2.0] | 54% concordance | 100% concordance |
Values are median [interquartile rang]
SUVmax = Maximum standard uptake value