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. 2019 Dec 6;10:2706. doi: 10.3389/fmicb.2019.02706

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Copyright © 2019 Li, Yao, Guo, Crits-Christoph, Mayes, Hervey, Lebeis, Banfield, Hurst, Hettich and Pan.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Phytohormone modulation, nutrient transportation, quorum sensing, and methanol metabolism in the four ¹³C-labeled microorganisms. Enzymes in purple boxes are labeled with triangles for encoded genes and circles for expressed proteins in these microorganisms. The triangles and circles are color-coded for each microorganism. MDH: NAD-dependent methanol dehydrogenase, Act: methanol dehydrogenase activator, FdhA: glutathione-independent formaldehyde dehydrogenase, FD: formate dehydrogenase, GFAE: glutathione-dependent formaldehyde-activating enzyme, SHGD: S-(hydroxymethyl)glutathione dehydrogenase, YeiG: S-formylglutathione hydrolase, laaM: tryptophan 2-monooxygenase, laaH: indole acetamide hydrolase, MetK: methionine adenosyltransferase, ACCD: 1-aminocyclopropane-1-carboxylate deaminase, FabD: malonyl CoA-acyl carrier protein transacylase, Soil: acyl-homoserine-lactone synthase, SoIR: transcriptional activator/quorum-sensing receptor, Dxs:1-deoxy-D-xylulose 5-phosphate synthase, Dxr: 2-C-methyl-D-erythritol 4-phosphate synthase, IspD: 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase, IspE: 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, IspF: 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, IspG: 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase, IspH: 4-hydroxy-3-methylbut-2-enyl diphosphate reductase, MiaA: tRNA isopentenyltransferase, LOG: cytokinin-specific phosphoribohydrolase ‘Lonely guy’, HMBPP: (E)-4-Hydroxy-3-methyl-but-2-enyl pyrophosphate, DMAPP: dimethylallyl pyrophosphate.