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. 2019 Dec 6;13:548. doi: 10.3389/fncel.2019.00548

Figure 5.

Figure 5

Cross-sections of the distal regenerated nerve segments at 4 and 8 weeks. Notes: representative images of regenerated axons at the distal nerve segment stained for NF-160 (green) in the groups of autograft (A), EVs+conduit (B) and PBS+conduit (C) at 4 weeks and autograft (D), EVs+conduit (E) and PBS+conduit (F) at 8 weeks. The upper right corner of the images (A–F) is higher magnifications of the boxed area in (A–F). Quantifications of the total number of the regenerated axons in the cross-sections at 4 weeks (G) and 8 weeks (H); n = 4 per group, scale bars: (A–F) 100 μm. The results are expressed as the mean ± SEM. One-way analysis of variance (ANOVA) test with Tukey’s post hoc test was used to examine the significance of results. ***p < 0.005 for comparison with the PBS+conduit, $p < 0.05 and $$p < 0.01 for comparison with the autograft group. Abbreviations: EVs, extracellular vesicles.