Figure 7.

Western blot results showing effects of exposure to low and high doses (2 and 10 mg/kg) of PM2.5 on hippocampal cAMP response element binding protein (CREB) and brain‐derived neurotrophic factor (BDNF) protein expression in immature and mature rats. (a) Representative images showing the expression levels of p‐CREB, CREB, and BDNF proteins in the hippocampus of immature and mature rats. Ctl, control group; High, high‐dose group; Low, low‐dose group; NS, saline group. (b–c) Quantitative analyses of CREB phosphorylation and BDNF expression level in each group. *p < .05 compared with saline group, **p < .01 compared with saline group, ***p < .001 compared with saline group. n = 6 per group