Table II.
Univariate analysis of factors associated with survival of patients with IDH1 wild-type glioblastoma multiforme.
| A, Overall survival | |||
|---|---|---|---|
| Variable | HR | 95% CI | P-value |
| Sex (male vs. female) | 0.754 | 0.435–1.269 | 0.526 |
| Age (≥60 vs. <60) | 1.857 | 1.113–2.648 | 0.038 |
| RLIP76 (high vs. low) | 1.986 | 1.045–2.976 | 0.008 |
| MTD (≥5 cm vs. <5 cm) | 0.776 | 0.418–1.397 | 0.716 |
| Resection degree | 0.039 | ||
| Total vs. partly | 0.324 | 0.098–0.912 | 0.023 |
| Subtotal vs. partly | 0.275 | 0.078–0.936 | 0.032 |
| B, Progression-free survival | |||
| Variable | HR | 95% CI | P-value |
| Sex (male vs. female) | 0.684 | 0.468–1.078 | 0.493 |
| Age (≥60 vs. <60) | 1.568 | 1.213–2.336 | 0.042 |
| RLIP76 (high vs. low) | 1.756 | 1.129–2.743 | 0.008 |
| MTD (≥5 cm vs. <5 cm) | 0.721 | 0.356–1.463 | 0.841 |
| Resection degree | 0.047 | ||
| Total vs. partly | 0.411 | 0.0618–0.985 | 0.031 |
| Subtotal vs. partly | 0.178 | 0.043–0.574 | 0.013 |
Univariate analysis, Cox proportional hazards regression model (n=98). Significant P-values are denoted in bold font. IDH1, isocitrate dehydrogenase 1; RLIP76, ralA binding protein 1; MTD, mean tumor diameter; HR, Hazard ratio; CI, confidence interval.