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. 2019 Oct 25;43(1):41–54. doi: 10.3892/or.2019.7389

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Copyright: © Xu et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 4. — Effect of iRhom1 and iRhom2 knockdown on HeLa cells. (A) Effect of iRhom1 and iRhom2 knockdown on apoptosis was presented as flow cytometry, with Annexin V staining and fluorescence-activated cell sorting analysis. (B) Effect of iRhom1 and iRhom2 knockdown on cell cycle progression, based on flow cytometry. **P<0.05, ***P<0.01 relative to shCtrl (iRhom/NC). iRhom1, inactive rhomboid protein 1; iRhom2, inactive rhomboid protein 2.