. 2019 Oct 25;43(1):41–54. doi: 10.3892/or.2019.7389

Table II.

Multivariate analysis of prognostic factors for patients with cervical cancer (n=83).

OS

Parameters	Hazard ratio	P-value	95%CI
Age, years	1.047	0.916	0.443–2.476
≤45
>45
Histology	0.97	0.903	0.597–1.576
Adenocarcinoma
Squamous carcinoma
Small cell carcinoma
Adenosquamous carcinoma
Clinical stage (FIGO)	1.778	0.027^a	1.069–2.598
I
II
Lymph node metastasis	0.475	0.152	0.156–1.335
Positive
Negative
Parametrium invasion	1.767	0.342	0.546–5.714
Positive
Negative
iRhom1	2.737	0.119	0.771–9.712
iRhom2	4.374	0.033^a	1.130–16.937
Ki-67	1.904	0.251	0.634–5.719

PFS

Age, years	1.2	0.68	0.506–2.846
≤45
>45
Histology	0.986	0.956	0.597–1.630
Adenocarcinoma
Squamous carcinoma
Small cell carcinoma
Adenosquamous carcinoma
Clinical stage (FIGO)	1.892	0.014^a	1.137–3.147
I
II
Lymph node metastasis	0.403	0.106	0.134–1.213
Positive
Negative
Parametrium invasion	1.429	0.545	0.450–4.539
Positive
Negative
iRhom1	3.037	0.085	0.858–10.753
iRhom2	4.074	0.036^a	1.097–15.129
Ki-67	1.876	0.272	0.611–5.759

Bold values are statistically significant (P<0.05). OS, overall survival; iRhom1, inactive rhomboid protein 1; iRhom2, inactive rhomboid protein 2; PFS, progression-free survival.