Table II.
Optimized differentially expressed proteins between groups.
| Protein ID | Protein | Fold change (ACBP-OXA/C) | P-value |
|---|---|---|---|
| Q8IZZ8 | Antithrombin (fragment) | 1.33 | 0.0012 |
| B7Z8Q4 | Hemopexin | 2.54 | 0.00126 |
| D6RBJ7 | Vitamin D-binding protein | 2.81 | 0.0016 |
| Q96RG4 | Insulin receptor substrate 2 insertion mutant (fragment) | 1.3 | 0.0018 |
| E5RJK7 | LYR motif-containing protein 2 | 1.23 | 0.0045 |
| A8MW49 | Fatty acid-binding protein | 4.8 | 0.0053 |
| Q99988 | Growth/differentiation factor 15 | 1.42 | 0.0054 |
| Q9BWT3 | Poly(A) polymerase gamma | 1.32 | 0.0055 |
| A0A087WVA8 | Testis-expressed sequence 2 protein | 1.39 | 0.0056 |
| Q8TB52 | F-box only protein 30 | 1.33 | 0.0066 |
| Q7Z6E9 | E3 ubiquitin-protein ligase RBBP6 | 1.21 | 0.0066 |
| Q9P1Y5 | Calmodulin-regulated spectrin-associated protein 3 | 1.24 | 0.008 |
| B3KRB7 | Inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta | 1.45 | 0.008 |
| Q9ULR3 | Protein phosphatase 1H | 1.29 | 0.009 |
| B4DQK1 | Autophagy-related protein 7 | 1.22 | 0.0179 |
| Q5T985 | Inter-alpha-trypsin inhibitor heavy chain H2 | 1.74 | 0.02 |
| O60701 | UDP-glucose 6-dehydrogenase | 1.21 | 0.02 |
| Q5T440 | Putative transferase CAF17 | 1.27 | 0.022 |
| Q53RD8 | Putative uncharacterized protein LOC84524 (fragment) | 1.37 | 0.023 |
| Q5T123 | SH3 domain-binding glutamic acid-rich-like protein 3 | 1.26 | 0.023 |
| Q15125 | 3-beta-hydroxysteroid-Delta(8), Delta(7)-isomerase | 1.42 | 0.024 |
| I3L1D4 | RNA-binding protein fox-1 homolog 1 (fragment) | 1.23 | 0.025 |
| B4DMX4 | Alpha-fetoprotein | 2.03 | 0.025 |
| P48506 | Glutamate-cysteine ligase catalytic subunit | 1.25 | 0.026 |
| P01023 | Alpha-2-macroglobulin | 2.3 | 0.027 |
| A0A024R172 | Leukotriene B4 12-hydroxydehydrogenas | 1.22 | 0.028 |
| B4DTK6 | RNA polymerase I-specific transcription initiation factor RRN3 | 1.24 | 0.028 |
| I3L2L5 | Mapk-regulated corepressor-interacting protein 1 | 1.27 | 0.028 |
| F6KPG5 | Albumin (fragment) | 2.94 | 0.029 |
| B3KM35 | Beta-1,4-galactosyltransferase 4 | 1.27 | 0.031 |
| B4E1V0 | Lactotransferrin | 1.68 | 0.034 |
| B7Z8R6 | AMBP protein | 2.11 | 0.039 |
| B7Z2S5 | Thioredoxin reductase 1 | 1.22 | 0.038 |
| P07477 | Trypsin-1 | 1.24 | 0.039 |
| Q5HYD9 | Putative uncharacterized protein DKFZp686M0619 (fragment) | 1.2 | 0.041 |
| Q9BW34 | EEF1D protein (fragment) | 1.28 | 0.041 |
| O15173 | Membrane-associated progesterone receptor component 2 | 1.21 | 0.04 |
| H7C5E8 | Serotransferrin (fragment) | 2.02 | 0.042 |
| P09669 | Cytochrome c oxidase subunit 6C | 1.22 | 0.044 |
| Q71UM5 | 40S ribosomal protein S27-like | 1.79 | 0.046 |
| P46013 | Proliferation marker protein Ki-67 | 0.076 | 0.0008 |
| Q9H3K6 | BolA-like protein 2 | 0.79 | 0.0009 |
| P16402 | Histone H1.3 | 0.809 | 0.0016 |
| B4DMI9 | Discs large homolog 7 | 0.8 | 0.0048 |
| D3YTB1 | 60S ribosomal protein L32 (fragment) | 0.8 | 0.005 |
| H3BQH3 | Kelch domain-containing protein 4 (fragment) | 0.744 | 0.0079 |
| B3KMT5 | SGT1 protein | 0.81 | 0.009 |
| P63218 | Guanine nucleotide-binding protein G(I)/G(S)/G(O) | 0.8 | 0.009 |
| Q9Y3U8 | 60S ribosomal protein L36 | 0.8 | 0.009 |
| P11388 | DNA topoisomerase 2-alpha | 0.78 | 0.114 |
| P0CJ79 | Zinc finger protein 888 | 0.77 | 0.012 |
| B3KQT6 | Tetraspanin-13 | 0.81 | 0.012 |
| B2RA70 | Tyrosine-protein kinase | 0.82 | 0.015 |
| Q5T7U1 | General transcription factor 3C polypeptide 5 | 0.81 | 0.015 |
| A8YQF4 | MHC class I antigen (fragment) | 0.71 | 0.017 |
| Q15397 | Pumilio homolog 3 | 0.799 | 0.018 |
| P50914 | 60S ribosomal protein L14 | 0.82 | 0.019 |
| G5E9A6 | Ubiquitin carboxyl-terminal hydrolase 11 | 0.74 | 0.02 |
| P39023 | 60S ribosomal protein L3 | 0.83 | 0.002 |
| P31350 | Ribonucleoside-diphosphate reductase subunit M2 | 0.8 | 0.02 |
| M0R0F0 | 40S ribosomal protein S5 (fragment) | 0.82 | 0.025 |
| Q6N075 | Molybdate-anion transporter | 0.82 | 0.026 |
| Q8TDD1 | ATP-dependent RNA helicase DDX54 | 0.74 | 0.031 |
| O60287 | Nucleolar pre-ribosomal-associated protein 1 | 0.81 | 0.031 |
| C9K025 | 60S ribosomal protein L35a (fragment) | 0.82 | 0.031 |
| Q9ULW0 | Targeting protein for Xklp2 | 0.79 | 0.032 |
| A0A0A0MRW6 | Nucleolar protein 6 | 0.79 | 0.033 |
| Q92876 | Kallikrein-6 | 0.77 | 0.033 |
| A8K800 | Homo sapiens brix domain containing 1 | 0.79 | 0.038 |
| P60604 | Ubiquitin-conjugating enzyme E2 | 0.77 | 0.038 |
| A8K7A2 | Cell division cycle associated 8 | 0.81 | 0.044 |
| S4R456 | 40S ribosomal protein S15 (fragment) | 0.78 | 0.04 |
| A8K4B4 | Homo sapiens nucleolar and spindle associated protein 1 | 0.8 | 0.04 |
| O75487 | Glypican-4 | 0.76 | 0.04 |
| A0A087WXM6 | 60S ribosomal protein L17 (fragment) | 0.81 | 0.04 |
| Q8TDN6 | Ribosome biogenesis protein BRX1 homolog | 0.73 | 0.04 |
| Q96HP0 | Dedicator of cytokinesis protein 6 | 0.73 | 0.04 |
The proteins listed above did not exhibit differences in expression between the ACBP- and OXA-treated groups. ACBP, anticancer bioactive peptides; OXA, oxaliplatin; C, control.