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. 2019 Oct 22;10:2412. doi: 10.3389/fmicb.2019.02412

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Copyright © 2019 Islam, Fernando and Saha.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Variability in metabolic fluxes under different community objective functions. (A) Visual representation showing the choice of different community-level objective functions. The density functions (right) show the insignificance of the variations in exchange flux space upon optimizing for different objective functions, i.e., maximizing total community biomass, maximizing total Short-chain Fatty Acids (SCFA) production, maximizing total complex carbohydrate uptake, minimizing total Methane and carbon-di-oxide production, and maximizing total sugar production by the community: (B) R. flavefaciens, (C) P. ruminicola, and (D) M. gottschalkii. The bandwidth is the standard deviation of the smoothing kernel of the density function.