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. 2019 Dec 2;13(1):86–91. doi: 10.1016/j.tranon.2019.09.007

Table 1.

Prevalence of Chlamydial trachomatis IgG, cHSP60 IgG, and Anti-MUC1 IgG in Prospective Blood Samples in Women With High-Grade Serous Ovarian Cancer and Matched Controls

Antibodies Cases
Controls
P
n n+ (%+) n n+ (%+)
 C. trachomatis IgG 92 15 (16.3%) 358 61 (17.0%) 0.87
  1–7.3 years 46 8 (17.4%) 176 24 (13.6%) 0.52
  >7.3 years 69 14 (20.3%) 270 45 (16.7%) 0.48
 cHSP60 IgG§ 92 25 (27.2%) 358 102 (28.5%) 0.80
  1–7.3 years 46 16 (34.8%) 176 54 (30.7%) 0.59
  >7.3 years 69 18 (26.1%) 270 67 (24.8%) 0.83
 Anti-MUC1 IgG 92 11 (12.0%) 359 24 (6.7%) 0.09
  1–7.3 years 46 2 (4.3%) 177 13 (7.3%) 0.74#
  >7.3 years 69 9 (13.0%) 270 17 (6.3%) 0.06

Abbreviations: C. trachomatis IgG = Chlamydia trachomatis IgG; cHSP60 IgG = chlamydial Heat Shock Protein 60 IgG; MUC1 = mucin 1.

Chi-square test.

One control was not evaluated because of technical problems.

The same individual might have samples in both the 1–7.3 years or >7.3 years subgroups.

§

Cutoff for cHSP60 IgG was defined as the mean optical density value of the negative control plus 0.350 and results are presented as positive (+) or negative (−).

Cutoff for high anti-MUC1 IgG level was considered as an optical density of ≥1.0.

#

Fisher's exact test.