Table 1.
Prevalence distribution of pfdhfr and pfdhps gene mutations among two groups.
| Gene | Codon | % (n) of isolates |
P | |
|---|---|---|---|---|
| Western Africa | Central Africa | |||
| pfdhpr | N = 165 | N = 43 | ||
| N51I | 86.1 (142) | 90.7 (39) | 0.611 | |
| C59R | 90.3 (149) | 93.0 (40) | 0.799 | |
| S108N | 93.3 (154) | 93.0 (40) | 1 | |
| I164L | 11.5 (19) | 4.7 (2) | 0.295 | |
| pfdhps | N = 147 | N = 40 | ||
| I431V | 0.7 (1) | 0.0 (0) | 1.000 | |
| S436 A/F | 57.1 (84) | 45.0 (18) | 0.211 | |
| A437G | 87.8 (129) | 70.0 (28) | 0.015* | |
| K540 E/N | 12.9 (19) | 10.0 (4) | 0.820 | |
| A581G | 11.6 (17) | 0.0 (0) | 0.052 | |
| A613 S/T | 10.9 (16) | 5.0 (2) | 0.414 | |
*:P < 0.05.