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. 2019 Nov 28;29:101397. doi: 10.1016/j.redox.2019.101397

Table 3.

Functional annotation of genes affected by AP diet.

Go term p-value q-value
Biological processes
GO:0055093 response to hyperoxia 0.0012 0.1004
GO:0071496 cellular response to external stimulus 0.0016 0.1004
GO:0044763 single-organism cellular process 0.0052 0.2077
GO:0031668 cellular response to extracellular stimulus 0.0057 0.2017
GO:0044424 intracellular part 0.0062 0.1140
GO:0045137 development of primary sexual characteristics 0.0089 0.2017
GO:0042493 response to drug 0.0091 0.2017
GO:0019538 protein metabolic process 0.0097 0.2017
Pathways
R-HSA-418360 Platelet calcium homeostasis 0.0017 0.0540
De novo fatty acid biosynthesis De novo fatty acid biosynthesis 0.0036 0.0540
R-HSA-75105 Fatty Acyl-CoA Biosynthesis 0.0052 0.0540
R-HSA-72695 Formation of the ternary complex, and subsequently, the 43 S complex 0.0060 0.0540
R-HSA-72649 Translation initiation complex formation 0.0075 0.0540
R-HSA-72702 Ribosomal scanning and start codon recognition 0.0075 0.0540
R-HSA-72662 Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43 S 0.0077 0.0540
WP3942 PPAR signaling pathway 0.0087 0.0540
WP1982 Sterol Regulatory Element-Binding Proteins (SREBP) signaling 0.0087 0.0540
path:hsa 03320 PPAR signaling pathway - Homo sapiens (human) 0.0097 0.0543

Transcripts showed significant changes after a false-discovery rate correction (p < 0.05) were subjected for gene ontology and pathway analyses. Functional annotation was done with ConsensusPathDB.