Fig. 4.

From the Pioneer study using the Seno Imagio linear system: example of upgrading BI-RADS 3 to 4A or higher. Images in a 71-year-old woman: (A) internal US image showing mass assessed as BI-RADS 3. (B) PA/US combined map reveals abundant intensely deoxy-Hb within the tumor interior, deoxy-Hb blush within the echogenic rim that represents the tumor boundary zone (arrowheads) and radiating peripheral artery (green) and vein (red) (arrows). BI-RADS 3 assessment was upgraded to 4A or 4B. Biopsy revealed triple-negative IDC. (Reproduced with permission of the authors and publishers.)