Fig. 11.

Using the University of Twente PAM planar system: example of PA mass appearance seen in 63 year old patient with infiltrating ductal carcinoma (IDC). (A) The breast was tilted during the PA measurement to position the lesion favorably within the detector's FOV of 85 × 90 mm². The lesion in the average intensity projection (AIP) PA image, is visible as an irregular, high contrast, 29 mm mass. The lesion co-localized well with the lesion in the X-ray image (not shown). The lesion also co-localized well with (B) the AIP MRI image after tilting the PA image. The dashed box indicates the FOV where PA image is acquired. The MR appearance is described as an irregularly shaped mass (C) post-surgery H&E stained specimen revealed the presence of a 34 mm grade 2 IDC. (D) The CD31 stained tumor slide shows the microvascularity spread over the entire lesion supporting the mass-appearance observed in PA and MR images. It is intriguing that the patterns in (A)–(D) appear roughly similar in appearance. (Reproduced with permission of the authors and publisher.)