Fig. 2.

Electrocardiograms of WT and Gly790del DSC2 KI mice. A, B. Representative recordings of electrocardiogram (ECG) in WT and KI mice at baseline. The ECG was recorded and analyzed using a digital acquisition and analysis system (Power Lab/4SP). Data represent means ± SEM of 8–10 mice. C. (left) ECG recordings for 24 h. Ventricular arrhythmia was rarely seen in both WT and KI mice. (right) Incidence of ventricular tachyarrhythmia (VT) after intraperitoneal injection of epinephrine (2 mg/kg body weight) and caffeine (120 mg/kg body weight) (Epi/Caff). D. Summarized data of arrhythmia event. Only homozygous G790del/G790del mice showed arrhythmias but not frequently.