TABLE 4.

Correlation coefficients and significance between the abnormal directional connectivity and tinnitus characteristics in tinnitus patients.

Brain region	Tinnitus duration	THQ	SAS	SDS
L-NAc to L-IFG	r = 0.108	r = 0.112	r = −0.149	r = 0.051
	p = 0.477	p = 0.401	p = 0.323	p = 0.736
L-NAc to L-cuneus	r = 0.180	r = 0.068	r = −0.276	r = −0.115
	p = 0.232	p = 0.652	p = 0.063	p = 0.446
R-NAc to L-MFG	r = 0.080	r = 0.357	r = 0.132	r = −0.051
	p = 0.597	p = 0.015∗	p = 0.384	p = 0.712
R-NAc to R-OFC	r = 0.599	r = 0.118	r = −0.025	r = 0.007
	p < 0.001∗	p = 0.435	p = 0.867	p = 0.963
R-MFG to L-NAc	r = 0.099	r = 0.626	r = −0.032	r = −0.051
	p = 0.514	p < 0.001∗	p = 0.834	p = 0.735
R-MTG to L-NAc	r = 0.245	r = −0.030	r = −0.026	r = −0.184
	p = 0.119	p = 0.841	p = 0.862	p = 0.221
R-MFG to R-NAc	r = 0.225	r = −0.013	r = 0.029	r = −0.158
	p = 0.128	p = 0.932	p = 0.851	p = 0.293
R-MTG to R-NAc	r = 0.205	r = −0.138	r = 0.064	r = −0.134
	p = 0.171	p = 0.360	p = 0.672	p = 0.375

^∗p < 0.05. THQ, tinnitus handicap questionnaires; SAS, self-rating anxiety scale; SDS, self-rating depression scale; NAc, nucleus accumbens; IFG, inferior frontal gyrus; MFG, middle frontal gyrus; OFC, orbitofrontal cortex; MTG, middle temporal gyrus; L, left; R, right.