Table 2.
Median dMRI measures | Groupwise Comparisons | ||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|
FT | VPT | HG-IVH | PHH | Sig. | FT: VPT | FT: HG-IVH | FT: PHH | VPT: HG-IVH | VPT: PHH | HG-IVH: PHH | |
Lateral ventricular perimeter | |||||||||||
FA | 0.27±0.05 | 0.23±0.04 | 0.21±0.04 | 0.16±0.05 | <0.001* | <0.001* | <0.001* | <0.001* | 0.100 | <0.001* | 0.004* |
MD (μm2/s) | 1.46±0.09 | 1.47±0.08 | 1.55±0.11 | 1.58±0.15 | <0.001* | 1.000 | 0.011* | 0.027* | 0.008* | 0.034* | 1.000 |
AD (μm2/s) | 1.88±0.12 | 1.85±0.15 | 1.93±0.18 | 1.82±0.25 | 0.031* | 0.299 | 1.000 | 1.000 | 0.055 | 1.000 | 0.869 |
RD (μm2/s) | 1.24±0.15 | 1.29±0.12 | 1.38±0.10 | 1.48±0.15 | <0.001* | 0.057 | 0.003* | <0.001* | 0.014* | <0.001* | 0.048* |
Frontal occipital horn perimeter | |||||||||||
FA | 0.29±0.07 | 0.22±0.06 | 0.20±0.05 | 0.13±0.04 | <0.001* | <0.001* | <0.001* | <0.001* | 0.349 | <0.001* | <0.001* |
MD (μm2/s) | 1.59±0.11 | 1.66±0.19 | 1.73±0.14 | 1.77±0.24 | <0.001* | 0.022* | 0.003* | 0.102 | 0.213 | 0.700 | 1.000 |
AD (μm2/s) | 2.13±0.14 | 2.09±0.27 | 2.11±0.21 | 1.94±0.32 | 0.173 | 1.000 | 1.000 | 0.281 | 1.000 | 1.000 | 0.567 |
RD (μm2/s) | 1.33±0.17 | 1.45±0.18 | 1.56±0.15 | 1.66±0.24 | <0.001* | 0.002* | <0.001* | 0.007* | 0.118 | 0.007* | 0.869 |
All measures within the respective groups are medians ± standard deviations where necessary; One-way ANOVA was performed with Kruskal-Wallis test (Sig.). All groupwise comparisons performed by Wilcoxon signed rank family-wise comparisons. All p-values are Benjamini-Hochberg corrected with alpha level set at p <0.050 (*). FA = fractional anisotropy; MD = mean diffusivity; AD = axial diffusivity; RD = Radial diffusivity; PHH = post hemorrhagic hydrocephalus; HG-IVH = high grade intraventricular hemorrhage; VPT = very preterm; FT = full term.