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. 2019 Mar 5;35(3):251–259. doi: 10.1089/aid.2018.0234

FIG. 3.

FIG. 3.

Heat map showing distinct correlations between cervico-vaginal immune mediators, clinical parameters, and anti-HIV activity against HIV IIIB and BaL for (A) HIV-positive premenopausal, (B) HIV-positive postmenopausal, (C) HIV-positive postmenopausal on HRT, (D) HIV-negative premenopausal, (E) HIV-negative postmenopausal, and (F) HIV-negative postmenopausal women on HRT. Distinct network and clustering patterns between immune mediators were observed among groups. Each cell of the heat map is color coded based on Spearman correlation coefficients. Cells highlighted in shades of red indicate a positive association with darker shades representing stronger associations. Similarly, cells highlighted in shades of blue indicate a negative association with darker shades representing stronger associations. Statistically significant associations are denoted by ***p < 0.0001, **p < 0.001, and *p < 0.05.