Table 2.
Risk factors of mortality for IBD patients registered in the Catastrophic Illness Registry, Taiwan, 2001–2015
| UC (n = 2887) | CD (n = 919) | |||||
|---|---|---|---|---|---|---|
| Mortality (n = 214) | Survival (n = 2673) | p value | Mortality (n = 96) | Survival (n = 823) | p value | |
| n (%) | n (%) | n (%) | n (%) | |||
| Male sex | 143 (66.8) | 1644 (61.5) | 57 (59.4) | 574 (69.7) | 0.038 | |
| IBD registered age | < 0.001 | < 0.001 | ||||
| ≤ 39 | 24 (11.2) | 1094 (40.9) | 20 (20.8) | 523 (63.6) | ||
| 40–59 | 58 (27.1) | 1193 (44.6) | 26 (27.1) | 215 (26.1) | ||
| ≥ 60 | 132 (61.7) | 386 (14.4) | 50 (52.1) | 85 (10.3) | ||
| Operation | ||||||
| Colectomy | 1 (0.5) | 8 (0.3) | 0.501 | 1 (1.0) | 5 (0.6) | 0.485 |
| Colostomy | 31 (14.5) | 91 (3.4) | < 0.001 | 21 (21.9) | 52 (6.3) | < 0.001 |
| Exploratory laparotomy | 4 (1.9) | 9 (0.3) | 0.012 | 9 (9.4) | 16 (1.9) | < 0.001 |
| Ileostomy | 17 (7.9) | 61 (2.3) | < 0.001 | 8 (8.3) | 19 (2.3) | 0.004 |
| Comorbidity | ||||||
| Hypertension | 94 (43.9) | 580 (21.7) | < 0.001 | 37 (38.5) | 129 (15.7) | < 0.001 |
| Diabetes | 48 (22.4) | 278 (10.4) | < 0.001 | 19 (19.8) | 68 (8.3) | < 0.001 |
| Hyperlipidemia | 42 (19.6) | 557 (20.8) | 0.674 | 20 (20.8) | 101 (12.3) | 0.019 |
| COPD | 41 (19.2) | 188 (7.0) | < 0.001 | 10 (10.4) | 48 (5.8) | 0.081 |
| Hepatitis | 19 (8.9) | 232 (8.7) | 0.921 | 7 (7.3) | 55 (6.7) | 0.829 |
| EIM | ||||||
| Uveitis | 0 (0.0) | 90 (3.4) | 0.006 | 0 (0.0) | 23 (2.8) | 0.159 |
| Psoriasis | 10 (4.7) | 126 (4.7) | 0.978 | 2 (2.1) | 54 (6.6) | 0.111 |
| Erythema nodosum | 2 (0.9) | 20 (0.8) | 0.763 | 1 (1.0) | 24 (2.9) | 0.504 |
| Arthritis | 21 (9.8) | 172 (6.4) | 0.057 | 7 (7.3) | 77 (9.4) | 0.507 |
| Cholangitis | 7 (3.3) | 20 (0.8) | 0.003 | 4 (4.2) | 11 (1.3) | 0.062 |
| Deep vein thrombosis | 5 (2.3) | 27 (1.0) | 0.083 | 5 (5.2) | 11 (1.3) | 0.019 |
| Complication | ||||||
| Fistula | 26 (12.2) | 355 (13.3) | 0.638 | 13 (13.5) | 245 (29.8) | < 0.001 |
| Abdominal wall abscess | 11 (5.1) | 96 (3.6) | 0.249 | 7 (7.3) | 114 (13.9) | 0.072 |
| Cancer | ||||||
| Colorectal cancer | 10 (4.7) | 11 (0.4) | < 0.001 | 3 (3.1) | 5 (0.6) | 0.042 |
| Liver cancer | 9 (4.2) | 5 (0.2) | < 0.001 | 2 (2.1) | 0 (0.0) | 0.011 |
| Hospitalization | ||||||
| Pneumonia | 96 (44.9) | 114 (4.3) | < 0.001 | 36 (37.5) | 56 (6.8) | < 0.001 |
| Urinary tract infection | 69 (32.2) | 174 (6.5) | < 0.001 | 25 (26.0) | 86 (10.5) | < 0.001 |
| Sepsis | 122 (57.0) | 171 (6.4) | < 0.001 | 57 (59.4) | 112 (13.6) | < 0.001 |