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IL-26 promotes monocyte differentiation into osteoclasts with RANKL. Peripheral blood CD14+ monocytes (n = 3) were cultured with 25 ng/mL macrophage colony-stimulating factor (M-CSF) only (-) or with M-CSF (25 ng/mL) plus 1 ng/mL RANKL and/or 100 ng/mL IL-26. Images are representative of three independent experiments. **P < 0.01. IL interleukin, RANKL receptor activator of nuclear factor-kappaB ligand, CD cluster designation
