Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2019 Dec 12;21:283. doi: 10.1186/s13075-019-2070-0

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s). 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

PMC Copyright notice

Fig. 6 — IL-26-pretreated RA-FLSs induce osteoclastogenesis from peripheral blood monocytes. a RA-FLSs (n = 3) were preincubated with 100 ng/mL IL-26 for 72 h and then co-cultured with CD14⁺ monocytes from peripheral blood in the presence of macrophage colony-stimulating factor. After a 21-day culture, tartrate-resistant acid phosphatase (TRAP)⁺ multinucleated cells were counted. The image is representative of three independent experiments. b mRNA levels of osteoclast markers from differentiated osteoclasts according to real-time polymerase chain reaction (n = 3). Data were normalized against β-actin expression and represent the mean ± standard error of the mean of three independent experiments. **P < 0.01; ***P < 0.005. IL interleukin, RA rheumatoid arthritis, FLSs fibroblast-like synoviocytes, CD cluster designation