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. 2019 Nov 13;19(1):33–44. doi: 10.3892/etm.2019.8193

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Copyright: © Eweda et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 5. — Light micrographs of heart tissue. The (A) control and sesame lignans-treated rats (C) exhibited normal myocardial fiber architecture, with branching muscle fibers and centrally located oval nuclei. (Ba and Bb) Sections of heart tissue treated with BPA exhibited a loss of normal architecture, widespread fragmentation and muscle fiber degeneration. Inflammatory and mast cells (black circle) were present in the connective tissue, along with a congested blood vessel (dotted arrow), vacuoles (black arrow) and branches of thickened coronary vessels. (D) Histological alterations induced after BPA-treatment were markedly reduced when treated with BPA and sesame lignans (H&E staining; magnification, ×400). BPA, bisphenol A; c.a. coronary artery.