Table III.
Effect of orally administered BPA and/or sesame lignans on the liver oxidant and antioxidant status of rats.
| Animal treatment | ||||
|---|---|---|---|---|
| Parameters | C-group | B-group | S-group | BS-group |
| MDA (nmol/gm tissue) | 438.80±11.73 | 626.80±35.62a | 223.80±16.03a,b | 325.20±8.96a,b |
| GSH (nmol/mg protein) | 19.04±0.96 | 8.76±1.12a | 36.57±2.66a,b | 23.35±0.43b |
| GR (mu/mg protein) | 15.01±0.93 | 8.72±0.39a | 17.75±0.92a,b | 12.44±0.76a,b |
| GPx (mu/mg protein) | 644.75±20.19 | 403.72±11.35a | 838.40±27.72a,b | 658.40±13.41b |
| SOD (U/mg protein) | 4.44±0.19 | 2.28±0.27a | 5.31±0.32a,b | 3.68±0.35b |
Data are presented as mean ± SE.
a
P<0.05 vs. the control group
b
P<0.05 vs. the BPA-treated group. BPA, bisphenol A; MDA, malondialdehyde; GSH, reduced glutathione; GR, glutathione reductase; GPx, glutathione peroxidase; SOD, superoxide dismutase; C-group, control group; B-group, BPA-treated group; S-group, sesame lignans-treated group; BS-group, BPA and sesame lignans-treated group.