Table 3.
Comparison of left ventricular systolic and diastolic function at rest
| Controls (n = 24) |
CSFP ExECG (−) (n = 24) | CSFP ExECG (+) (n = 6) | P-value | |
|---|---|---|---|---|
| LV end-diastolic diameter (mm) | 47.12 ± 3.63 | 47.02 ± 4.87 | 47.63 ± 2.77 | 0.83 |
| LV end-systolic diameter (mm) | 31.36 ± 3.51 | 32.39 ± 4.13 | 32.06 ± 2.80 | 0.61 |
| LV end-diastolic volume (ml) | 80.30 ± 15.02 | 78.60 ± 13.81 | 77.52 ± 18.93 | 0.78 |
| LV ejection fraction (%) | 63.00 ± 4.20 | 63.20 ± 3.70 | 65.00 ± 4.00 | 0.15 |
| LV GLS (%) | −21.26 ± 2.74 | −19.98 ± 2.32* | −19.70 ± 2.38* | 0.01 |
| LA volume index (ml/m2) | 27.06 ± 5.12 | 29.99 ± 3.57* | 30.56 ± 5.64* | 0.03 |
| Mitral E (cm/s) | 73.85 ± 16.47 | 72.34 ± 16.65 | 61.72 ± 15.75*# | < 0.001 |
| Mitral A (cm/s) | 74.63 ± 16.81 | 71.28 ± 13.33 | 67.07 ± 13.59* | 0.08 |
| Mitral E/A | 1.12 ± 0.33 | 1.09 ± 0.28 | 0.94 ± 0.21* | 0.05 |
| Mitral septal e’ (cm/s) | 7.40 ± 2.05 | 6.97 ± 1.76 | 6.10 ± 1.74* | 0.01 |
| Mitral lateral e’ (cm/s) | 10.41 ± 2.70 | 9.55 ± 2.18 | 8.07 ± 2.87*# | < 0.001 |
| Mitral average e’ (cm/s) | 8.94 ± 2.19 | 8.26 ± 1.80 | 7.09 ± 2.14*# | < 0.001 |
| Mitral average E/e’ | 8.59 ± 2.20 | 8.99 ± 2.09 | 9.31 ± 2.87 | 0.33 |
| Tricuspid regurgitation velocity (m/s) | 1.66 ± 0.69 | 1.80 ± 0.54 | 1.93 ± 0.59 | 0.29 |
Values shown are mean ± SD. Abbreviations: LV, left ventricle; GLS, global longitudinal strain; LA, left atrium; E, early diastolic flow velocity; A, late diastolic flow velocity; e’, early diastolic annular velocity
*P < 0.05 vs. controls; #P < 0.05 vs. CSFP ExECG (−)