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. 2019 Dec 13;16:264. doi: 10.1186/s12974-019-1665-3

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© The Author(s). 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 3 — EA treatment increases the metabolic activity of 5XFAD mice as determined by microPET scans. a Representative microPET images in specific brain regions (frontal cortex, cortex, and hypothalamus) at 60 min after intravenous injection of ¹⁸F-FDG on the day after the last EA treatment. The right panel shows the reference for the specific brain region. b Quantitative analysis of ROI-based ¹⁸F-FDG uptake (SUV) in the frontal cortex, cortex, hypothalamus, and hippocampus of each group (n = 3–4/group). Data are presented as means ± SEM (*p < 0.05, **p < 0.01)