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. 2019 Dec 12;50:109. doi: 10.1186/s13567-019-0725-0

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© The Author(s) 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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The effect of lsr operon on transcriptional profiles of virulence-related genes. The qPCR results showed that there was no significant difference of fimH mRNA level between lsr mutant strains and APEC94 or lsr-APEC94Δlsr (p > 0.05). However, the mRNA levels of five genes (fliD, flhA, dosP, pgaA and fhuD) were significantly decreased in lsr mutant strain, as compared to APEC94 (p < 0.05).