Table 2.
Recovery sleep | No sleep intervention | |||||||
---|---|---|---|---|---|---|---|---|
LP 1 x̄ a | LP 2 x̄ | FC | p | LP 1 x̄ | LP 2 x̄ | FC | p | |
NFL | 325 | 305 | 0.94 | 0.231 | 198 | 194 | 0.98 | N/A |
GFAp | 183 | 188 | 1.03 | 0.641 | 236 | 231 | 0.98 | N/A |
T-tau | 215 | 395 | 1.83 | 0.008 | 208 | 317 | 1.52 | N/A |
P-tau | 39 | 59 | 1.51 | 0.006 | 31 | 43 | 1.39 | N/A |
Ab38 | 2640 | 3611 | 1.37 | 0.005 | 2353 | 2930 | 1.25 | N/A |
Ab40 | 7432 | 9434 | 1.27 | 0.006 | 6249 | 7117 | 1.14 | N/A |
Ab42 | 913 | 1198 | 1.31 | 0.003 | 719 | 878 | 1.22 | N/A |
YKL-40 | 56,718 | 72,363 | 1.28 | 0.039 | 56,978 | 71,639 | 1.26 | N/A |
LP 1 x̄ and LP 2 x̄ represent average absolute concentrations in the first and second lumbar puncture, measured in pg/mL. p represents probability value calculated by paired two-tailed t-test
YKL-40 chitinase-3-like protein, NFL neurofilament light, GFAp glial fibrillary acidic protein, T Tau total tau. P-tau phosphorylated tau FC fold change of each biomarker
aPreviously published data [2]