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. 2019 Dec 13;16:37. doi: 10.1186/s12987-019-0157-2

Table 2.

CSF biomarker concentrations

Recovery sleep No sleep intervention
LP 1 x̄ a LP 2 x̄ FC p LP 1 x̄ LP 2 x̄ FC p
NFL 325 305 0.94 0.231 198 194 0.98 N/A
GFAp 183 188 1.03 0.641 236 231 0.98 N/A
T-tau 215 395 1.83 0.008 208 317 1.52 N/A
P-tau 39 59 1.51 0.006 31 43 1.39 N/A
Ab38 2640 3611 1.37 0.005 2353 2930 1.25 N/A
Ab40 7432 9434 1.27 0.006 6249 7117 1.14 N/A
Ab42 913 1198 1.31 0.003 719 878 1.22 N/A
YKL-40 56,718 72,363 1.28 0.039 56,978 71,639 1.26 N/A

LP 1 x̄ and LP 2 x̄ represent average absolute concentrations in the first and second lumbar puncture, measured in pg/mL. p represents probability value calculated by paired two-tailed t-test

YKL-40 chitinase-3-like protein, NFL neurofilament light, GFAp glial fibrillary acidic protein, T Tau total tau. P-tau phosphorylated tau FC fold change of each biomarker

aPreviously published data [2]