Table 4.
Longitudinal analyses of MF, SF and PF with functional disability, nursing home referral and mortality
| Functional Disability | Nursing Home Referral | Mortality | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| N | % | OR (95% CI) | P | N | % | OR (95% CI) | P | N | /1000 py (95% CI) | HR (95% CI) | P | |
| Total | 1174 | 2387 | 2387 | |||||||||
| Unadjusted | ||||||||||||
| Physical frailty | 72/496 | 14.5 | 1.89 (1.30–2.73) | 0.001 | 31/1154 | 2.7 | 2.59 (1.35–4.98) | 0.004 | 268/1154 | 21.47 (19.05–24.20) | 2.29 (1.86–2.81) | < 0.001 |
| Mental frailty | 36/256 | 14.1 | 1.47 (0.97–2.22) | 0.068 | 23/657 | 3.5 | 2.95 (1.62–5.37) | < 0.001 | 174/657 | 24.60 (21.21–28.55) | 2.09 (1.72–2.55) | < 0.001 |
| Social frailty | 28/172 | 16.3 | 1.75 (1.11–2.76) | 0.015 | 23/438 | 5.3 | 5.09 (2.79–9.28) | < 0.001 | 117/438 | 24.76 (20.66–29.68) | 1.89 (1.53–2.35) | < 0.001 |
| Adjusted1 | ||||||||||||
| Physical frailty | 1.49 (1.01–2.20) | 0.044 | 1.54 (0.75–3.17) | 0.238 | 1.51 (1.21–1.89) | < 0.001 | ||||||
| Mental frailty | 1.12 (0.71–1.74) | 0.629 | 1.68 (0.86–3.26) | 0.129 | 1.46 (1.18–1.81) | < 0.001 | ||||||
| Social frailty | 1.27 (0.83–2.08) | 0.331 | 3.43 (1.77–6.65) | < 0.001 | 1.32 (1.05–1.65) | 0.018 | ||||||
| Unadjusted | ||||||||||||
| Robust without MF or SF | 37/499 | 7.4 | 1.00 | 6/884 | 0.7 | 1.00 | 88/884 | 8.64 (7.01–10.65) | 1.00 | |||
| Robust with MF and/or SF | 19/179 | 10.6 | 1.48 (0.83–2.65) | 0.184 | 7/349 | 2.0 | 3.00 (1.00–8.98) | 0.050 | 48/349 | 11.82 (8.91–15.68) | 1.35 (0.95–1.91) | 0.099 |
| Pre-frail or Frail without SF or MF | 43/318 | 13.5 | 1.95 (1.23–3.11) | 0.005 | 4/626 | 0.6 | 0.94 (0.26–3.35) | 0.925 | 103/626 | 14.82 (12.21–17.97) | 1.74 (1.31–2.31) | < 0.001 |
| Pre-frail or Frail with MF and/or SF | 29/178 | 16.3 | 2.43 (1.44–4.09) | 0.001 | 27/528 | 5.1 | 7.89 (3.23–19.23) | < 0.001 | 165/528 | 29.84 (25.62–34.76) | 3.48 (2.69–4.51) | < 0.001 |
| Adjusted2 | ||||||||||||
| Robust without MF or SF | 1.00 | 1.00 | 1.00 | |||||||||
| Robust with MF and/or SF | 1.20 (0.66–2.19) | 0.555 | 3.91 (1.08–14.10) | 0.037 | 1.40 (0.99–2.00) | 0.061 | ||||||
| Pre-frail or Frail without SF or MF | 1.59 (0.98–2.58) | 0.059 | 1.33 (0.33–5.41) | 0.689 | 1.52 (1.14–2.03) | 0.005 | ||||||
| Pre-frail or Frail with MF and/or SF | 1.65 (0.95–2.87) | 0.078 | 7.17 (2.32–22.2) | 0.001 | 2.25 (1.70–2.97) | < 0.001 | ||||||
1Model includes: gender, age, comorbidity, physical frailty, mental frailty and social frailty
2Model includes: gender, age and comorbidity