Table 5.

Association between athlete age and AT8 p-tau pathology

	Neurons with NFT	Neurons with punctate p-tau	Total neuronsa	Neurite clusters	Dystrophic neurites	Total pathologyb
Age at death
PrCc	0.64d ***	0.55 ***	0.65 ***	0.66 ***	0.55 ***	0.63 ***
EC	0.65 ***	0.49 **	0.61 ***	0.63 ***	0.49 **	0.60 ***
DG	0.60 ***	0.63 ***	0.67 ***	0.51 **	0.63 ***	0.66 ***
CA3	0.57 ***	0.18	0.48 **	0.59 ***	0.50 **	0.53 ***
CA1	0.58 ***	0.22	0.48 **	0.65 ***	0.53 ***	0.61 ***
Sub	0.61 ***	0.27	0.56 ***	0.49 **	0.46 **	0.57 ***
PrS	0.58 ***	0.57 ***	0.62 ***	0.49 **	0.53 ***	0.59 ***
Years from retirement to death
PrC	0.52 ***	0.40 *	0.52 ***	0.52 ***	0.41 **	0.49 **
EC	0.53 ***	0.49 **	0.50 **	0.54 ***	0.38 *	0.50 **
DG	0.42 *	0.62 ***	0.54 **	0.45 **	0.54 **	0.56 ***
CA3	0.48 **	0.15	0.38 *	0.45 **	0.37	0.40 *
CA1	0.46 **	0.19	0.38 *	0.58 ***	0.46 **	0.53 ***
Sub	0.60 ***	0.30	0.56 ***	0.52 ***	0.45 **	0.56 ***
PrS	0.52 ***	0.47 **	0.54 ***	0.43 **	0.54 ***	0.57 ***

^aNeurons with NFT and punctate p-tau neurons

^bNeurons with NFT, punctate p-tau neurons, neurite clusters, dystrophic neurites

^cPrC Perirhinal cortex, EC Entorhinal cortex, DG Dentate gyrus, CA3 Hippocampus CA3, CA1 Hippocampus CA1, Sub Subiculum, PrS Pre−/parasubiculum

^dSpearman rank order correlation with Benjamini-Hochberg false discovery critical values, * p < 0.05, ** p < 0.01, *** p < 0.001