CR749391 expression in gastric cancer cells and its effect on cell proliferation in vitro. (A and B) MTT assays were performed to determine the proliferation of (A) si-CR749391-transfected GES-1 cells or (B) pcDNA3.1/CR749391-transfected BGC-823 cells. (C-F) The apoptotic rates of (C and D) GES-1 cells transfected with si-CR749391 and (E and F) BGC-823 cells transfected with pcDNA3.1/CR749391 vector were detected by flow cytometry. Values are expressed as the mean ± standard deviation from three independent experiments. *P<0.05; **P<0.01. si-CR749391, small interfering RNA targeting long non-coding RNA CR749391; miR, microRNA; pcDNA3.1/CR749391, overexpression plasmid for CR749391; NC, negative control; OD 490, optical density at 490 nm; PI, propidium iodide; FITC, fluorescein isothiocyanate; Q, quadrant; LR, lower right; UL, upper left.