Figure 4.
Effect of CR749391 on gastric cancer cell migration and invasion in vitro. Transwell assays were performed to investigate changes in cell migration and invasion. (A and B) GES-1 cells were transfected with si-CR749391 or si-NC, and (C and D) BGC-823 cells were transfected with pcDNA3.1/CR749391 vector or empty vector control, and then subjected to Transwell assays. Magnification, ×100. The data are expressed as the mean ± standard deviation of three independent experiments. *P<0.05 and **P<0.01. si-CR749391, small interfering RNA targeting long non-coding RNA CR749391; pcDNA3.1/CR749391, overexpression plasmid for CR749391; NC, negative control.