Figure 4.

Effect of miR-144-5p overexpression on TNF-α, IL-6 and IL-8 levels in the THP-1 macrophage cell culture supernatant. (A) Cells transfected with miR144-5p mimic or mimic control were treated with LPS for 24 h, following which ELISA was used to measure the secretion of TNF-α, (B) IL-6 and (C) IL-8 in THP-1 macrophages. Data are presented as the mean ± SD. **P<0.01 vs. NC group. miR, microRNA; IL, interleukin; TNF-α, tumor necrosis factor-α; NC, mimic negative control; LPS, lipopolysaccharide.