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. 2019 Jul 1;36(14):2190–2199. doi: 10.1089/neu.2018.6269

Table 4.

Summary of Beta Coefficients Between Plasma Tau and All Diffusion Tensor Imaging Regions of Interest and the Whole Brain

  Uncomplicated mild (n = 47) Complicated mild (n = 19) Moderate+ (n = 22)
  FA MD RD AD FA MD RD AD FA MD RD AD
WHOLE BRAIN .176 .002 −.076 .154 .125 .094 .019 .173 .383 −.350 −.385 −.181
F MAJOR −.014 −.390b −.223 −.408b −.288 .010 .113 −.199 .149 −.353 −.262 −.329
F MINOR .249 −.032 −.157 .171 −.080 .106 .119 .039 .395 −.316 −.369 −.104
L ATR .172 −.007 −.092 .124 −.119 .021 .092 −.103 .269 −.288 −.331 −.060
L CAB .120 .201 .118 .257 .178 .137 .081 .185 .196 −.018 −.056 .073
L CCG .293 .165 −.133 .374a .211 .126 −.061 .314 .438 −.264 −.419 .128
L CST .047 .149 .058 .178 .066 .001 −.062 .059 .260 −.506a −.511a −.254
L ILF −.195 −.015 .095 −.209 .102 .222 .155 .231 .537a −.087 −.275 .354
L SLFP .205 .148 −.026 .262 .140 −.041 −.107 .078 .250 −.455a −.458a −.350
L SLFT .166 .252 .062 .301a .244 .099 −.127 .257 .310 −.419 −.433 −.245
L UNC .166 −.041 −.111 .105 −.182 .427 .440 .311 .467a −.174 −.294 .120
R ATR .159 .178 .067 .262 .089 .096 .044 .151 .392 −.327 −.438a −.044
R CAB .179 −.123 −.165 −.012 .161 .109 .023 .243 .029 .062 .032 .101
R CCG .129 .095 −.055 .180 .120 −.109 −.139 −.036 .312 −.420 −.394 −.166
R CST .060 .047 −.007 .089 −.106 .201 .179 .070 .129 −.315 −.288 −.231
R ILF −.141 −.216 −.074 −.304a .181 .047 −.037 .128 .611b −.245 −.413 .145
R SLFP −.003 .002 .016 −.020 .060 .142 .049 .170 .057 −.247 −.234 −.212
R SLFT .137 −.013 −.081 .109 .068 .143 .044 .183 −.061 −.278 −.183 −.378
R UNC −.041 .313a .227 .281 .007 .053 .024 .075 .305 −.235 −.271 −.060

FA, fractional anisotropy; MD, median diffusivity; RD, radial diffusivity; AD, axial diffusivity; CCF major, corpus callosum-forceps major; CCF Minor, corpus callosum-forceps minor; ATR, anterior thalamic radiation; CAB, cingulum–angular (infracallosal) bundle; CCF, cingulum–cingulate gyrus (supracallosal) bundle; CST, corticospinal tract; ILF, inferior longitudinal fasciculus; SLFP, superior longitudinal fasciculus-parietal bundle; SLFT, superior longitudinal fasciculus-temporal bundle; UNF, uncinate fasciculus.

a

p < 0.05.

b

p < 0.01.