Table 5B.

Differences in the Biomarker Levels in Different Patient Groups

	Mann U, non-isolated all severities TBI CT+ vs. isolated all severities TBI CT+ (median levels, pg/mL)	Mann U, non-isolated all severities TBI CT− vs. isolated all severities TBI CT− (median levels, pg/mL)	Mann U, non-isolated mTBI CT+ vs. isolated mTBI CT+ (median levels, pg/mL)	Mann U, non-isolated mTBI CT− vs. isolated mTBI CT− (median levels, pg/mL)
Aβ40	0.449 (21.4 vs. 24.7)	0.533 (15.7 vs. 17.0)	0.775 (17.0 vs. 20.1)	0.521 (14.2 vs. 16.9)
Aβ42	0.438 (20.0 vs. 18.5)	0.888 (15.9 vs. 15.7)	0.753 (17.4 vs. 17.6)	0.898 (15.9 vs. 15.7)
GFAP	0.916 (5890 vs. 6840)	0.001 (1140 vs. 204)	0.118 (1830 vs. 604)	0.001 (1140 vs. 186)
H-FABP	0.023 (16800 vs. 6720)	0.002 (8440 vs. 4080)	0.298 (15400 vs. 5670)	0.004 (7250 vs. 3880)
IL-10	0.386 (1.10 vs. 0.86)	0.024 (0.79 vs. 0.37)	0.014 (1.10 vs. 0.41)	0.090 (0.73 vs. 0.34)
NF-L	0.871 (48.4 vs. 57.6)	0.034 (13.6 vs. 8.66)	0.036 (19.1 vs. 14.0)	0.070 (13.0 vs. 8.23)
S100B	0.107 (122 vs. 83.5)	0.851 (81.1 vs. 85.9)	0.019 (92.3 vs. 51.4)	0.824 (81.1 vs. 83.5)
tau	0.216 (11.0 vs. 6.83)	0.002 (2.35 vs. 1.53)	0.005 (4.29 vs. 1.79)	0.001 (2.44 vs. 1.51)

Statistically significant p values are in bold.

GCS, Glasgow Coma Scale; TBI, traumatic brain injury; CT, computed tomography; SD, standard deviation; Mann U, p value from Mann-Whitney U-test; Aβ40, β-Amyloid isoform 1–40; Aβ42 β-Amyloid isoform 1–42; GFAP, glial fibrillary acidic protein; H-FABP, heart fatty-acid binding protein; IL-10, interleukin 10; NF-L neurofilament light; S100B, S100 calcium-binding protein B; Mann U, p value from Mann-Whitney U-test.