Table 2.
Canonical Pathways Annotation from Global Proteome Associated with Myelin Sheath and Axonal Injury after LIB Injury
| Canonical pathway | Differentially expressed proteins | ||||
|---|---|---|---|---|---|
| ID | Name | 3 h | 24 h | 7 DPI | 30 DPI |
| mmu04360 | Axon guidance | CDK5 | CDK5, GNAI3, MAPK3, NTNG1 | NA | NA |
| 3.55E-01 | 3.68E-01 | 9.37E-01 | 9.75E-01 | ||
| mmu04810 | Regulation of actin cytoskeleton | NCKAP1 | MYH9, WASL, NCKAP1, MAPK3, WASF2 | RRAS2 | NCKAP1 |
| 2.86E-02 | 2.03E-05 | 5.94E-01 | 4.25E-01 | ||
| mmu04071 | Sphingolipid signaling pathway | NA | GNAI3, MAPK3 | GNAQ | GNAQ |
| 2.86E-02 | 2.03E-05 | 5.94E-01 | 4.25E-01 | ||
| mmu04514 | Cell adhesion molecules (CAMs) | NA | NRXN3, NEGR1, NTNG1 | NA | NA |
| 6.38E-01 | 6.49E-01 | 1.00E+00 | 8.41E-01 | ||
LIB, low-intensity blast; DPI, days post-injury.